Related Experiment Video
Updated: Jul 20, 2026

Contrast Imaging in Mouse Embryos Using High-frequency Ultrasound
Published on: March 4, 2015
Diagnostic and imaging considerations: role of viability
1Department of Cardiovascular Medicine, Northwick Park Hospital, Watford Road, Harrow Middlesex, HA1 3UJ, United Kingdom. roxy.senior@virgin.net
Assessing myocardial viability is crucial for heart failure patients with left ventricular dysfunction undergoing revascularisation. This review details non-invasive testing methods, their pros, and cons to guide optimal treatment strategies.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- Left ventricular systolic dysfunction is a key feature of heart failure.
- Coronary artery disease is the primary cause of left ventricular systolic dysfunction in developed countries.
- Revascularisation is a treatment option for heart failure patients with significant left ventricular dysfunction.
Purpose of the Study:
- To review the role of non-invasive testing for myocardial viability in patients with left ventricular systolic dysfunction and heart failure.
- To outline the advantages and disadvantages of various myocardial viability assessment techniques.
Main Methods:
- Literature review focusing on non-invasive diagnostic techniques.
- Analysis of current evidence regarding the impact of myocardial viability on revascularisation outcomes.
- Discussion of limitations in existing research and clinical trials.
Main Results:
- Myocardial viability influences outcomes after revascularisation.
- Multiple non-invasive techniques exist to assess myocardial viability, each with limitations.
- Significant uncertainty remains regarding the optimal strategy due to limited data.
Conclusions:
- Non-invasive testing for myocardial viability is important for guiding revascularisation decisions in heart failure.
- Further research and randomized trials are needed to clarify the optimal diagnostic and therapeutic strategies.
- Understanding the pros and cons of each viability assessment technique is essential for clinical practice.
Related Concept Videos
Radiological Investigation II: MRI and Ventilation Perfusion Scan
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Imaging Studies II: Ultrasonography
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Imaging Studies VII: Vascular Imaging
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...

