Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Heart Failure I: Introduction01:27

Heart Failure I: Introduction

Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
Heart Failure VII: Nursing Interventions01:30

Heart Failure VII: Nursing Interventions

The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The effect of long-term tafamidis treatment on quality of life in people with transthyretin amyloid cardiomyopathy (ATTR-CM): A plain language summary.

Future cardiology·2024
Same author

Oxygen therapy and palliative care in patients with heart failure. Response.

Revista espanola de cardiologia (English ed.)·2020
Same author

Consensus document and recommendations on palliative care in heart failure of the Heart Failure and Geriatric Cardiology Working Groups of the Spanish Society of Cardiology.

Revista espanola de cardiologia (English ed.)·2019
Same author

Exercise training in patients with ventricular assist devices: a review of the evidence and practical advice. A position paper from the Committee on Exercise Physiology and Training and the Committee of Advanced Heart Failure of the Heart Failure Association of the European Society of Cardiology.

European journal of heart failure·2018
Same author

Corrigendum to 'Role of cardiopulmonary exercise testing in clinical stratification in heart failure. A position paper from the Committee on Exercise Physiology and Training of the Heart Failure Association of the European Society of Cardiology' [Eur J Heart Fail 2018;20:3-15].

European journal of heart failure·2018
Same author

Role of cardiopulmonary exercise testing in clinical stratification in heart failure. A position paper from the Committee on Exercise Physiology and Training of the Heart Failure Association of the European Society of Cardiology.

European journal of heart failure·2017

Related Experiment Video

Updated: Jul 20, 2026

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models
07:49

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models

Published on: July 21, 2023

[Heart failure. Are women different?].

María G Crespo Leiro1, María J Paniagua Martín

  • 1Servicio de Cardiología, Area del Corazón, Complejo Hospitalario Univeristario Juan Canalejo, A Coruña, España. mcrelei@canalejo.org

Revista Espanola De Cardiologia
|August 30, 2006
PubMed
Summary

Heart failure is common in women, especially older women with preserved ejection fraction. Understanding sex-based differences in heart failure epidemiology and treatment is crucial for improving care.

Area of Science:

  • Cardiology
  • Women's Health
  • Clinical Medicine

Background:

  • Heart failure (HF) is a prevalent clinical syndrome, disproportionately affecting women, particularly the elderly and those with preserved ejection fraction.
  • Significant sex-based disparities exist in HF epidemiology, pathogenesis, treatment response, and quality of care.
  • While HF incidence is higher in men, prevalence increases with age in women, who appear to have a better prognosis, though underlying mechanisms remain unclear.

Purpose of the Study:

  • To highlight the significant differences in heart failure presentation, progression, and outcomes between women and men.
  • To underscore the need for further research into the specific aspects of heart failure in women.
  • To address the underrepresentation of women in clinical trials and its impact on understanding treatment efficacy.

Related Experiment Videos

Last Updated: Jul 20, 2026

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models
07:49

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models

Published on: July 21, 2023

Main Methods:

  • Review of epidemiological data on heart failure prevalence and incidence stratified by sex and age.
  • Analysis of factors contributing to sex-based differences in heart failure pathogenesis and prognosis.
  • Examination of clinical trial data regarding female participant inclusion and treatment response.

Main Results:

  • Women constitute the majority of the heart failure patient population, especially in older age groups and those with preserved ejection fraction.
  • Key differences observed in epidemiology, pathogenesis, and treatment response between sexes.
  • Women generally exhibit a better prognosis, but the reasons are not fully elucidated.
  • Underrepresentation of women in heart failure clinical trials limits evidence-based treatment guidelines for this demographic.

Conclusions:

  • Heart failure management requires a sex-specific approach due to distinct epidemiological and clinical characteristics in women.
  • Further research and inclusive clinical trial designs are essential to optimize heart failure treatment and outcomes for women.
  • Addressing disparities in care and research is critical for improving the health of the large female population affected by heart failure.