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Enhancing Prostate Tumor Biobanking Reliability with Improved Sampling Technique and Histological Characterization
Published on: November 17, 2023
Frozen tissue biobanks. Tissue handling, cryopreservation, extraction, and use for proteomic analysis
Christer Ericsson1, Bo Franzén, Monica Nistér
1Department of Oncology - Pathology, Karolinska Institutet, CCK R8:05, Karolinska University Hospital, Solna, 171 76 Stockholm, Sweden. christer.ericsson@ki.se
Acta Oncologica (Stockholm, Sweden)
|August 30, 2006
Abstract:
The potential and the limitations of protein analysis of tissue samples are surveyed. The complexity, concentration range and dynamics of the human proteome are reviewed, as is the effect of handling and cryopreservation. Protein extraction, solubilization, resolution and detection are discussed, in relation to the properties of the human proteome.
