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Acute effects of anticonvulsants on brain-stem auditory evoked potentials in rats
1Department of Neurology, Kanazawa Medical University, Kahoku-gun, Japan.
Electroencephalography and Clinical Neurophysiology
|June 1, 1990
Abstract:
Acute effects of various anticonvulsants on brain-stem auditory evoked potentials (BAEPs) in rats were tested. A high dose of phenytoin abolished all BAEP waves. Carbamazepine increased all 4 wave latencies. Phenobarbital and clonazepam increased the latencies of waves IV and III. Therefore, if BAEPs are to be used as an ancillary test for brain death, the possibility of significant effects of high dosages of anticonvulsants on BAEPs must be considered.