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Performing Custom MicroRNA Microarray Experiments
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Performing Custom MicroRNA Microarray Experiments

Published on: October 28, 2011

TM4 microarray software suite

Alexander I Saeed1, Nirmal K Bhagabati, John C Braisted

  • 1Department of Bioinformatics, The Institute for Genomic Research, Rockville, MD, USA.

Methods in Enzymology
|August 31, 2006
PubMed

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Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...