Related Experiment Videos
Localized purpura associated with lamotrigine
Catherine M Amlie-Lefond1, Judy L Felgenhauer, Alan D Leong
1Department of Neurology, Division of Pediatric Neurology, Medical College of Wisconsin, Milwaukee, 53226, USA. KLefond@mcw.edu
Abstract:
Antiepileptic drug hypersensitivity syndrome consists of fever, rash, and internal organ involvement and usually occurs within the first 2 months of initiation of therapy. This report describes a 13-year-old female with a right frontal high-grade glioma and complex partial seizures who developed localized purpura after 23 months of lamotrigine monotherapy. This case study is the second report of localized purpura after prolonged lamotrigine treatment suggesting this may be an atypical lamotrigine-induced drug reaction.
Related Concept Videos
Antiepileptic Drugs: Glutamate Antagonists
Endocarditis II: Clinical Features of Infective Endocarditis
Drug toxicity: Idiosyncratic Reactions
Graves' Disease I: Introduction
Drug Toxicity: Allergic Reactions
Drugs for Peptic Ulcer Disease: Sucralfate as Mucosal Protective Agents
In this scenario, mucosal protective agents like sucralfate play an essential role. Sucralfate, a complex of sulfated sucrose and aluminum hydroxide, demonstrates its usefulness in acidic conditions,...