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Isolated abducens nerve palsy complicating cytomegalovirus infection
Filippo Greco1, Rosaria Garozzo, Giovanni Sorge
1Department of Pediatrics, University of Catania, Catania, Italy. coicoico@hotmail.com
Insights
Cytomegalovirus infection can cause isolated abducens nerve palsy in children. Prompt ganciclovir treatment led to rapid recovery in an immunocompetent 5-year-old girl.
Area of Science:
- Pediatric Neurology
- Infectious Diseases
- Ophthalmology
Background:
- Isolated abducens nerve palsy is a rare neurological condition.
- Cytomegalovirus (CMV) is a common virus that can cause various health issues.
Observation:
- A 5-year-old immunocompetent female presented with isolated abducens nerve palsy.
- The palsy was associated with a cytomegalovirus infection.
Findings:
- Cytomegalovirus was detected in the cerebrospinal fluid using polymerase chain reaction.
- Treatment with ganciclovir resulted in rapid clinical improvement of the palsy.
Implications:
- This case suggests CMV infection as a potential cause of isolated abducens nerve palsy in children.
- Highlights the importance of considering viral etiologies in pediatric cranial nerve palsies.
- Demonstrates the efficacy of ganciclovir in treating CMV-induced neurological complications.
Abstract:
This report describes an immunocompetent 5-year-old female with isolated abducens nerve palsy complicating a cytomegalovirus infection and documented with polymerase chain reaction performed on cerebrospinal fluid; treatment with ganciclovir was associated with rapid clinical improvement. It may be the first report of cytomegalovirus detected in the central nervous system as a cause of isolated abducens nerve palsy.
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