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Updated: Jul 20, 2026

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
Published on: December 7, 2021
How do we compare hundreds of bacterial genomes?
Dawn Field1, Gareth Wilson, Christopher van der Gast
1Oxford Centre for Ecology and Hydrology, Oxford OX1 3SR, UK. dfield@ceh.ac.uk
Abstract:
The genomic revolution is fully upon us in 2006 and the pace of discovery is set to accelerate with the emergence of ultra-high-throughput sequencing technologies. Our complete genome collection of bacteria and archaea continues to grow in number and diversity, as genome sequencing is applied to an array of new problems, from the characterization of the pan-genome to the detection of mutation after experimentation and the exploration of microbial communities in unprecedented detail. The benefits of large-scale comparative genomic analyses are driving the community to think about how to manage our public collections of genomes in novel ways.
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