Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Drugs Affecting GI Tract Motility: Bulk-Forming and Stimulant Laxatives01:22

Drugs Affecting GI Tract Motility: Bulk-Forming and Stimulant Laxatives

Laxatives enhance bowel movements and alleviate constipation. They augment the stool's bulk, stimulate intestinal muscle contractions, draw water into the intestines, or soften the stool. There are five key types of laxatives: bulk laxatives, stimulant laxatives, osmotic laxatives, stool softeners, and lubricant laxatives.
Bulk-forming laxatives, such as psyllium, methylcellulose, and polycarbophil, absorb water in the intestine, increasing stool bulk and promoting bowel movement. This makes...
Drugs Affecting GI Tract Motility: Other Laxatives01:20

Drugs Affecting GI Tract Motility: Other Laxatives

Laxatives are primarily used to alleviate constipation, a common gastrointestinal disorder characterized by infrequent bowel movements and difficulty passing stools. They work by various mechanisms to increase the volume or frequency of bowel movements. The primary modes of action of laxatives include increasing stool bulk, softening the stool, stimulating intestinal motility, and osmotically drawing water into the intestines.
Osmotic or saline laxatives, like magnesium hydroxide or milk of...
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transmission of methicillin-resistant Staphylococcus aureus via deceased donor liver transplantation confirmed by whole genome sequencing.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2014
Same author

Dialysis-associated steal syndrome.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2013
Same author

Measurement of the t-channel single top quark production cross section in pp collisions at √s=7  TeV.

Physical review letters·2011
Same author

Tacrolimus enhances the invasion potential of hepatocellular carcinoma cells and promotes lymphatic metastasis in a rat model of hepatocellular carcinoma: involvement of vascular endothelial growth factor-C.

Transplantation proceedings·2011
Same author

Indications of suppression of excited Υ states in Pb-Pb collisions at √(s(NN))=2.76 TeV.

Physical review letters·2011
Same author

Generation of a sheared plasma rotation by emission, propagation, and absorption of drift wave packets.

Physical review letters·2011

Related Experiment Videos

Surgery for slow transit constipation: are we helping patients?

M Zutshi1, T L Hull, R Trzcinski

  • 1Department of Colorectal Surgery, Cleveland Clinic Foundation, Desk A-30, 9500 Euclid Avenue, Cleveland, OH 44195, USA. zutshim@ccf.org

International Journal of Colorectal Disease
|September 1, 2006
PubMed
Summary

Surgery for slow transit constipation offers long-term benefits for many patients, with 77% reporting improvement. However, mental health aspects of quality of life may be impacted, necessitating careful patient selection.

Related Experiment Videos

Area of Science:

  • Gastroenterology
  • Colorectal Surgery
  • Surgical Outcomes

Background:

  • Long-term outcomes following surgical intervention for slow transit constipation (STC) remain debated.
  • Assessing the long-term quality of life (QoL) is crucial for understanding the full impact of STC surgery.

Purpose of the Study:

  • To evaluate the long-term quality of life (QoL) in patients who underwent colectomy with ileorectal anastomosis for slow transit constipation.
  • To identify factors influencing QoL and surgical outcomes in this patient cohort.

Main Methods:

  • Retrospective review of medical records for patients who had colectomy with ileorectal anastomosis (1983-1998).
  • Data collection included preoperative, operative, and postoperative details.
  • Long-term QoL assessment using the Short-Form (SF)-36 survey and a custom symptom questionnaire.

Main Results:

  • A total of 69 patients were analyzed with a median follow-up of 10.8 years.
  • Long-term complications occurred in 46% of patients, including small bowel obstruction (20%).
  • While physical QoL (SF-36 physical component) was comparable to healthy individuals, mental QoL (SF-36 mental component) was significantly lower, particularly in vitality and social functioning.

Conclusions:

  • Colectomy with ileorectal anastomosis can lead to long-term improvement in symptoms for a majority of patients (77% reported benefit).
  • Preoperative symptoms may persist post-surgery, and potential complications should be considered.
  • The mental health component of QoL warrants attention in the long-term management of patients undergoing surgery for STC.