Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The IMGT/HLA and IPD databases.

James Robinson1, Matthew J Waller, Sylvie C Fail

  • 1Anthony Nolan Research Institute, Royal Free Hospital, Hampstead, London, United Kingdom.

Human Mutation
|September 1, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Establishing a living systematic review of characterisation and parameter reporting in lithium-ion and lithium-sulfur cathode research.

Discover electrochemistry·2026
Same author

Recommendations for HLA Genotyping Data Standards and Clinical Laboratory Staffing Considerations.

HLA·2026
Same author

Do conditional marketing authorisations actually accelerate patient access? Time-to-access of conditional vs. standard marketing authorisations in Italy, Spain, and Germany.

Journal of pharmaceutical policy and practice·2026
Same author

Phase I multi-center clinical and biomarker study of the dual-action androgen receptor inhibitor ONCT-534.

Investigational new drugs·2026
Same author

Nomenclature for Factors of the HLA System, 2026.

HLA·2026
Same author

Experimental quantification of resistance to subsidence conferred by endplate-specific expandable implants in anterior lumbar interbody fusion.

Journal of orthopaedic surgery and research·2026
Same journal

RETRACTION: "Differential Effects of AKT1(p.E17K) Expression on Human Mammary Luminal Epithelial and Myoepithelial Cells".

Human mutation·2026
Same journal

Diagnostic Yield of Genome Sequencing in an Iranian Exome-Negative Autosomal-Recessive Intellectual Disability Cohort.

Human mutation·2026
Same journal

Exploring the Functional Impact of Individual <i>DDX41</i> Variants With a Fast and Robust Cell-Based Method.

Human mutation·2026
Same journal

Modeling the Effects of Single Nucleotide Polymorphisms (SNPs) on the Structure and Function of the Human <i>RET</i> Gene: An In Silico Study.

Human mutation·2026
Same journal

Driver Mutation Subtypes Differentially Shape Immune Evasion Landscapes in Melanoma: An AI-Driven Inflammatory Pathway Model Implicating CCNE1.

Human mutation·2026
Same journal

Comment on "When the Outcome Contains the Exposure: Methodological Limits of a Genome-Wide Cross-Trait Analysis of Type 2 Diabetes and MASLD".

Human mutation·2026
See all related articles

The IMGT/HLA database is a key resource for human major histocompatibility complex (HLA) sequences. The Immuno Polymorphism Database (IPD) expands this by offering specialized data on immune system genes.

Area of Science:

  • Immunogenetics
  • Bioinformatics
  • Molecular Biology

Background:

  • The IMGT/HLA database has served as a central repository for human major histocompatibility complex (HLA) allele sequences since 1998.
  • It is recognized as a primary information source for studying HLA sequences.
  • The Immuno Polymorphism Database (IPD) is a collection of specialized databases focused on polymorphic genes within the immune system.

Purpose of the Study:

  • To provide a comprehensive overview of the IMGT/HLA database and the IPD.
  • To highlight the growth and significance of these databases in immunological research.
  • To describe the different components within the IPD.

Main Methods:

  • Centralized data collection and curation of HLA allele sequences.

Related Experiment Videos

  • Development and maintenance of specialized databases for immune system genes.
  • Integration of sequence data with nomenclature from the WHO Nomenclature Committee for Factors of the HLA System.

    • Main Results:

    • The IMGT/HLA database has significantly grown and is a crucial resource for HLA sequence information.
    • The IPD comprises four distinct databases: IPD-KIR (killer-cell immunoglobulin-like receptors), IPD-MHC (major histocompatibility complex across species), IPD-HPA (human platelet antigens), and IPD-ESTDAB (tumor cell lines).

    Conclusions:

    • The IMGT/H LA and IPD databases are essential, continuously expanding resources for researchers studying immune system genetics and polymorphism.
    • These databases facilitate advancements in understanding immune responses, transplantation, and disease associations.