Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Attention-Deficit/Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.

Increased Intracranial Pressure l: Introduction

Increased Intracranial Pressure l: Introduction

Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...

Nightmares and Night Terrors

Nightmares and Night Terrors

Nightmares and night terrors represent two distinct types of sleep disturbances that differ in timing, characteristics, and the sleeper's recall of the event. Nightmares are vivid, disturbing dreams that usually awaken the sleeper from REM sleep, a stage of sleep where brain activity is high, and dreams are most frequent. Upon awakening, individuals often have detailed recollections of their nightmares, which can include themes of threats to survival, security, or self-esteem.
Nightmares often...

Chronic Pharyngitis

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...

Chronic Pancreatitis I: Introduction

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...

Chronic Pancreatitis I: Introduction

Chronic Pancreatitis I: Introduction

Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Cluster Analysis of Migraine-Associated Symptoms (CAMS) across the lifespan: a cross-sectional study.

BMC neurology·2026

Same author

Treatment outcomes in new daily persistent headache in children and adolescents.

Cephalalgia : an international journal of headache·2026

Same author

Patient reported trigger, not the speed of transition to continuous headache, is associated with headache-related disability in children: Results of a cross-sectional clinic-based study.

Cephalalgia : an international journal of headache·2026

Same author

Migraine-associated symptoms change with improvement in youth with migraine: A cohort study.

Cephalalgia reports·2026

Same author

Post-Traumatic Headache in Children and Genetic Risk of Migraine: An Observational Cohort Study.

Neurology. Genetics·2026

Same author

Headache-associated photophobia is more prevalent during winter: A cross-sectional study from a pediatric headache registry.

Headache·2026

Search research articles

Related Experiment Video

Updated: Jul 20, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Chronic daily headaches in children.

Andrew D Hershey¹, Marielle A Kabbouche, Scott W Powers

¹Headache Center, Division of Neurology, Cincinnati Children's Hospital, 3333 Burnet Avenue, MLC 2015, Cincinnati, OH 45229, USA. andrew.hershey@cchmc.org

Current Pain and Headache Reports

|September 2, 2006

Summary

Chronic daily headache (CDH) affects adults and children, often presenting as chronic migraine. Diagnosis requires careful evaluation, considering medication overuse, and treatment involves a multidisciplinary approach for better outcomes.

More Related Videos

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)

Published on: February 7, 2025

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Published on: July 29, 2021

Related Experiment Videos

Last Updated: Jul 20, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)

Published on: February 7, 2025

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Published on: July 29, 2021

Area of Science:

Neurology
Pediatrics
Headache Medicine

Background:

Chronic daily headache (CDH) is a growing concern in pediatric neurology.
Prevalence in children is not well-established, though it appears lower than the estimated 4% in adults.
CDH is defined as experiencing headaches on more than 15 days per month.

Purpose of the Study:

To review the diagnostic criteria and management of chronic daily headache in pediatric populations.
To highlight the complexities in diagnosing CDH, including medication overuse headache.
To emphasize the need for a comprehensive evaluation and treatment strategy.

Main Methods:

Review of International Classification of Headache Disorders (ICHD-II) criteria.
Contrast with Silberstein-Lipton criteria for CDH.
Discussion of diagnostic challenges and treatment modalities.

Main Results:

CDH diagnosis is complicated by medication overuse, requiring resolution before definitive diagnosis.
Pediatric CDH often exhibits migraine features but may not fully meet diagnostic criteria.
Secondary causes of headache must be ruled out through thorough history and physical examination.

Conclusions:

A multidisciplinary approach is essential for managing pediatric CDH.
Treatment includes acute care (avoiding medication overuse), preventive strategies, and biobehavioral therapy.
Effective management aims to reduce headache frequency and improve long-term outcomes.