Related Experiment Video
Updated: Jul 20, 2026

08:46
A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
Sudden infant death syndrome: no increased risk after immunisation
M M T Vennemann1, T Butterfass-Bahloul, G Jorch
1Institute of Legal Medicine, University of Münster, and Children's Hospital, University of Magdeburg, Germany. vennemam@uni-muenster.de
Vaccine
|September 2, 2006
Summary
This study found that immunisation is associated with a reduced risk of Sudden Infant Death Syndrome (SIDS). Vaccinations were less frequent and later in SIDS cases, with no increased risk observed post-immunisation.
Area of Science:
- Pediatrics
- Immunology
- Epidemiology
Background:
- Concerns persist regarding potential adverse effects of immunisations, including death, particularly with new vaccine introductions.
- Previous research indicates no association or a decreased risk of Sudden Infant Death Syndrome (SIDS) with immunisation.
Purpose of the Study:
- To investigate the association between immunisation and SIDS risk.
- To assess the safety of newly introduced vaccines in relation to SIDS.
Main Methods:
- A large-scale case-control study was conducted.
- Immunisation data from 307 SIDS cases and 971 controls were analyzed.
Main Results:
- SIDS cases exhibited less frequent and delayed immunisation compared to controls.
- No increased SIDS risk was detected within 14 days following immunisation.
- The hexavalent vaccines showed no association with an increased SIDS risk.
Conclusions:
- The findings support the hypothesis that immunisations may confer a protective effect against SIDS.
- This study adds to the evidence that routine immunisation is safe and potentially beneficial in reducing SIDS.
Related Concept Videos
Respiratory Syncytial Virus Disease
Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Vaccinations
Overview
Immunodeficiency Diseases
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...
There are three main causes of immunodeficiency disorders...
Development of Immunocompetence
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Poliomyelitis
Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Immunological Memory
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature is...
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature is...

