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Aspergillus meningitis following spinal anaesthesia for caesarean section in Colombo, Sri Lanka
N Rodrigo1, K N T Perera, R Ranwala
1dayarod7@sltnet.lk
Abstract:
We report six cases of Aspergillus meningitis after spinal anaesthesia for caesarean section administered in June and July 2005. Three patients died before a fungal infection was confirmed at the first post-mortem examination in August. Thereafter anti-fungal therapy was successful in saving the lives of the other three patients. Some syringes and spinal needles supplied to the hospitals concerned were found to be contaminated with Aspergillus fumigatus. Investigators found that medical supply storage facilities were substandard following the influx of donations after the tsunami of December 2004.
Insights
Six patients developed Aspergillus meningitis following spinal anesthesia for cesarean sections. Contaminated medical supplies and substandard storage conditions were identified as causes, with three patients succumbing before treatment.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Neuroscience
Background:
- Spinal anesthesia is a common procedure for cesarean sections.
- Aspergillus is an opportunistic fungal pathogen.
- Nosocomial infections can arise from contaminated medical equipment.
Observation:
- Six cases of Aspergillus meningitis occurred post-spinal anesthesia for cesarean section in mid-2005.
- Three patients died before diagnosis; the other three survived with antifungal therapy.
- Contaminated syringes and spinal needles with Aspergillus fumigatus were identified.
Findings:
- Substandard medical supply storage, exacerbated by post-tsunami donations, led to fungal contamination.
- Aspergillus fumigatus contamination of spinal procedure materials caused meningitis outbreaks.
- Prompt antifungal treatment improved outcomes in surviving patients.
Implications:
- Highlights the critical need for stringent sterilization and storage protocols for medical supplies.
- Underscores the risk of opportunistic fungal infections in healthcare settings.
- Emphasizes the importance of post-disaster supply chain management to prevent iatrogenic infections.
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