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Palmar-plantar erythema associated with combination chemotherapy
A Pagliuca1, R Kaczmarski, G J Mufti
1Academic Department of Haematological Medicine, King's College Hospital, Denmark Hill, London, UK.
Postgraduate Medical Journal
|March 1, 1990
Abstract:
We report three cases of a distinctive palmar-plantar erythema associated with the treatment of non-Hodgkin's lymphoma and acute myeloid leukaemia. The rash is characterized by a painful, sharply demarcated, intense erythema of the palms and/or soles followed by bulla formation, desquamation and healing. The eruption is self limiting in nature and did not adversely affect prognosis. Treatment need be neither altered nor stopped; only symptomatic measures are required.