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Cognitive impairment in bipolar II disorder
Carla Torrent1, Anabel Martínez-Arán, Claire Daban
1Clinical Institute of Neuroscience, University Hospital Clinic of Barcelona, Villarroel 170, 08036 Barcelona, Spain.
The British Journal of Psychiatry : the Journal of Mental Science
|September 2, 2006
Summary
Cognitive deficits are present in both bipolar I and bipolar II disorder patients compared to healthy individuals. Bipolar II disorder patients showed intermediate cognitive performance between bipolar I and controls.
Area of Science:
- Neuroscience
- Psychiatry
- Cognitive Psychology
Background:
- Persistent neurocognitive impairments are a known feature of bipolar disorder.
- Understanding these deficits is crucial for effective patient management.
Purpose of the Study:
- To compare cognitive performance across bipolar I disorder, bipolar II disorder, and healthy control groups.
- To identify specific cognitive domains affected in each group.
Main Methods:
- Included 71 euthymic patients (38 bipolar I, 33 bipolar II) and 35 healthy controls.
- Assessed neuropsychological variables including executive function, attention, and memory.
- Utilized tasks like DigitSpan, Trail Making Test, and Stroop interference.
Main Results:
- Both bipolar groups exhibited significant deficits in working memory and attention compared to controls.
- Bipolar II disorder patients demonstrated intermediate performance in verbal memory and executive functions.
- Cognitive impairment was more pronounced in the bipolar I group.
Conclusions:
- Cognitive impairment is evident in both bipolar I and II disorder subtypes.
- Subclinical depressive symptoms, early onset, and executive function deficits predict poor psychosocial functioning in bipolar II disorder.
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