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Updated: Jul 20, 2026

Assessment and Characterization of Hyaloid Vessels in Mice
Published on: May 15, 2019
Posterior hyaloid contracture in pediatric vitreoretinopathies
Mandar M Joshi1, Stefano Ciaccia, Michael T Trese
1Associated Retinal Consultants, William Beaumont Hospital, Royal Oak, Michigan, USA.
Background:
Retinal detachment in pediatric vasoproliferative disorders such as retinopathy of prematurity (ROP) and familial exudative vitreoretinopathy (FEVR) have an exudative and tractional component. Younger eyes have an especially adherent posterior hyaloid. Contraction of the posterior hyaloid interface may lead to tractional retinal detachment.
Methods:
Retrospective chart review of six eyes (four ROP, two FEVR) with diffuse contraction of the posterior hyaloid resulting in retinal detachment. Fundus photographs and optical coherence tomography findings (one eye) are presented.
Results:
Diffuse proliferation along the posterior hyaloid required extensive lamellar dissection at times aided by autologous plasmin enzyme. A diffuse, taut posterior hyaloid resulted in marked tractional component to retinal detachment.
Conclusions:
Recognition of hyaloid contracture will aid in the proper diagnosis and surgical planning and repair of eyes with pediatric vasoproliferative disorders.
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