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Chlorpyrifos toxicosis in two cats
1Department of Small Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens 30602.
Journal of Veterinary Internal Medicine
|May 1, 1990
Summary
Organophosphate (OP) compounds like chlorpyrifos can cause chronic toxicosis in cats, with symptoms worsening after diazepam. Prompt treatment with pralidoxime chloride (2-PAM) and atropine led to complete recovery.
Area of Science:
- Veterinary Toxicology
- Small Animal Medicine
- Environmental Health
Background:
- Organophosphate compounds are common insecticides and parasiticides.
- Chlorpyrifos, a long-acting organophosphate, is used in cattle but not recommended for cats.
- No prior clinical cases of feline chlorpyrifos toxicosis existed.
Observation:
- Two cases of chronic chlorpyrifos toxicosis in cats were documented.
- Cats exhibited chronic OP toxicosis symptoms prior to diazepam administration.
- Diazepam administration precipitated acute organophosphate toxicosis signs.
Findings:
- Chlorpyrifos toxicosis in cats presents with chronic and acute phases.
- Diazepam can exacerbate organophosphate toxicity in felines.
- Treatment with pralidoxime chloride (2-PAM) and atropine was effective.
Implications:
- Highlights the risks of off-label organophosphate use in cats.
- Informs veterinary treatment protocols for feline organophosphate poisoning.
- Underscores the importance of careful drug administration in toxicosis cases.