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Updated: Jul 20, 2026

Using Nicotine in a Silica-Exposed Mouse Model to Promote Lung Epithelial-Mesenchymal Transition
Published on: March 3, 2023
[Nicotine replacement therapy during pregnancy]
1Unidad Especializada en Tabaquismo, Dirección General de Salud Pública y Alimentación, Comunidad de Madrid, Madrid, España. victorina@ctv.es
Smoking during pregnancy significantly increases health risks for mothers and infants. Nicotine replacement therapy is recommended for pregnant smokers when other methods fail, with this review detailing its safe use.
Area of Science:
- Obstetrics and Gynecology
- Addiction Medicine
- Pharmacology
Context:
- Smoking remains a leading cause of pregnancy complications, affecting 20% in North America and 30-35% in Spain.
- Addressing smoking addiction is a critical priority for healthcare providers managing pregnant patients.
Purpose:
- To review the established indications and contraindications for nicotine replacement therapy (NRT) in pregnant women.
- To discuss safety considerations associated with NRT use during pregnancy.
Summary:
- NRT is a recommended intervention for pregnant smokers who have not succeeded with less invasive smoking cessation methods.
- The article provides a comprehensive overview of when to use and when to avoid NRT in this population.
- Key aspects of NRT safety during pregnancy are examined.
Impact:
- Provides essential guidance for healthcare professionals on managing smoking addiction in pregnant women.
- Aims to improve maternal and infant outcomes by promoting evidence-based cessation strategies.
- Facilitates informed decision-making regarding NRT for obstetric patients.
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