Related Experiment Video

Updated: Jul 20, 2026

Improved Preparation and Preservation of Hippocampal Mouse Slices for a Very Stable and Reproducible Recording of Long-term Potentiation
09:39

Improved Preparation and Preservation of Hippocampal Mouse Slices for a Very Stable and Reproducible Recording of Long-term Potentiation

Published on: June 26, 2013

LTP consolidation: substrates, explanatory power, and functional significance

Gary Lynch1, Christopher S Rex, Christine M Gall

  • 1Department of Psychiatry and Human Behavior, Gillespie Neuroscience Research Facility, University of California, Irvine, CA 92697-4292, USA. glynch@uci.edu

Neuropharmacology
|September 5, 2006
PubMed
Summary

This study proposes that the initial memory stabilization in long-term potentiation (LTP) involves cytoskeletal reorganization within dendritic spines. This process, triggered by theta bursts, leads to actin polymerization and spine stabilization, forming the basis of memory consolidation.

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