Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Murine Nasal Lavage Fluid Collection without Blood Contamination05:12

Murine Nasal Lavage Fluid Collection without Blood Contamination

1.7K
The present protocol describes a novel method for avoiding blood contamination in murine nasal lavage fluid (NLF). Since this method ensures the NLF collection without blood contamination, it allows for more accurate detections of immunological components and various respiratory...
1.7K
Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome03:40

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome

1.1K
OSTSS leads to pooled inflammatory mediators in the tear film, causing symptoms like epiphora and discomfort. Here, we present a case where therapeutic nasolacrimal lavage every 2 months resolved epiphora and itchiness, suggesting its efficacy as a therapeutic intervention for OSTSS. Additionally, we report subjective improvements in symptoms in 3 additional...
1.1K
Saline Lavage for Sampling of the Canine Nasal Immune Microenvironment04:35

Saline Lavage for Sampling of the Canine Nasal Immune Microenvironment

880
Saline nasal lavage can be used to sample the canine nasal immune microenvironment. Because the approach is relatively non-invasive and does not disrupt the nasal tissues, it can be performed serially. Cells and proteins collected from the nasal lavage technique can be processed for various laboratory analyses.
880
Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

2.9K
A protocol for conducting a challenge in an allergen exposure chamber (AEC) facility is presented. AECs have proven to be safe and effective tools for the induction of allergic symptoms or as an endpoint in the efficacy testing of allergen immunotherapy due to their ability to maintain stable particle concentrations and environmental...
2.9K
Reduced Itraconazole Concentration and Durations Are Successful in Treating Batrachochytrium dendrobatidis Infection in Amphibians06:49

Reduced Itraconazole Concentration and Durations Are Successful in Treating Batrachochytrium dendrobatidis Infection in Amphibians

12.0K
Batrachochytrium dendrobatidis infection in amphibians can be eliminated using a reduced concentration (0.0025%) and shorter duration (five minute baths for six days) of itraconazole than is generally used. Less mortality and fewer negative side effects were observed using this modified treatment...
12.0K
Intranasal Administration of CNS Therapeutics to Awake Mice07:15

Intranasal Administration of CNS Therapeutics to Awake Mice

61.4K
A method to intranasally administer drugs to awake mice for the purpose of targeting the brain is described. This method allows for repeat dosing over long periods using intranasal administration of drug without anesthesia, and nose-to-brain delivery with minimal systemic...
61.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Highlights from the 2025 Symposium of the Collegium Internationale Allergologicum.

The Journal of allergy and clinical immunology·2026
Same author

CD25 expression marks an activated mast cell population in human nasal polyposis.

The Journal of allergy and clinical immunology·2026
Same author

Tuft cells shape airway remodeling by eliciting OXGR1- and SOX9-dependent stem cell programs.

Nature communications·2026
Same author

Platelet-macrophage cooperation drives IL-33-dependent type 2 lung immunopathology in a sex-biased manner.

The Journal of allergy and clinical immunology·2026
Same author

Mast cell-specific CysLT2 receptor signaling inhibits cysteinyl leukotriene-dependent mast cell activation and type 2 allergic lung inflammation.

Cell reports·2025
Same author

Progenitor T cells drive chronic pulmonary type 2 inflammation.

bioRxiv : the preprint server for biology·2025

Related Experiment Video

Updated: Jan 8, 2026

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome
03:40

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome

Published on: April 25, 2025

1.1K

Asthma 2005-2006: bench to bedside.

Joshua A Boyce1

  • 1Department of Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, MA 02115, USA.

The Journal of Allergy and Clinical Immunology
|September 5, 2006
PubMed
Summary
This summary is machine-generated.

This review explores the complex syndrome of asthma, focusing on bronchial inflammation and airway hyperresponsiveness. It highlights recent insights into asthma pathogenesis to improve treatment strategies.

More Related Videos

Saline Lavage for Sampling of the Canine Nasal Immune Microenvironment
04:35

Saline Lavage for Sampling of the Canine Nasal Immune Microenvironment

Published on: December 27, 2024

880
Intranasal Administration of CNS Therapeutics to Awake Mice
07:15

Intranasal Administration of CNS Therapeutics to Awake Mice

Published on: April 8, 2013

61.4K

Related Experiment Videos

Last Updated: Jan 8, 2026

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome
03:40

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome

Published on: April 25, 2025

1.1K
Saline Lavage for Sampling of the Canine Nasal Immune Microenvironment
04:35

Saline Lavage for Sampling of the Canine Nasal Immune Microenvironment

Published on: December 27, 2024

880
Intranasal Administration of CNS Therapeutics to Awake Mice
07:15

Intranasal Administration of CNS Therapeutics to Awake Mice

Published on: April 8, 2013

61.4K

Area of Science:

  • Pulmonology
  • Immunology
  • Pathogenesis of Respiratory Diseases

Background:

  • Asthma is a common respiratory syndrome characterized by bronchial inflammation and airway hyperresponsiveness.
  • Significant gaps exist in understanding asthma's variable treatment responses and causative factors.
  • Phenotypic heterogeneity complicates asthma management and research.

Purpose of the Study:

  • To review recent advancements in understanding asthma pathogenesis.
  • To explore how new insights can inform asthma treatment development and selection.
  • To address the complexities of airway hyperresponsiveness and disease variability.

Main Methods:

  • Literature review of recent studies on asthma pathogenesis.
  • Analysis of current research on airway inflammation and hyperresponsiveness.
  • Synthesis of findings related to asthma treatment variability.

Main Results:

  • Emerging research provides new perspectives on the underlying mechanisms of asthma.
  • Understanding disease pathways is crucial for addressing treatment variability.
  • Latest insights offer potential for targeted therapeutic approaches.

Conclusions:

  • Continued research into asthma pathogenesis is vital for advancing patient care.
  • Novel therapeutic strategies may arise from a deeper understanding of asthma's complex mechanisms.
  • Addressing phenotypic variants is key to improving asthma control and treatment efficacy.