Related Experiment Video
Updated: Jul 20, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
Sleep restriction increases blood neutrophils, total cholesterol and low density lipoprotein cholesterol in
Myriam Kerkhofs1, Karim Zouaoui Boudjeltia, Patricia Stenuit
1Sleep Laboratory, CHU de Charleroi, Vésale Hospital, Free University of Brussels, Rue de Gozée 706, 6110 Montigny-le-Tilleul, Belgium. myriam.kerkhofs@chu-charleroi.be
Objectives:
This study examines the effects of sleep restricted to 4h for three consecutive nights on blood parameters known to be associated with cardiovascular risk in healthy postmenopausal women.
Material And Methods:
Ten healthy postmenopausal women aged 55-65 years treated with hormonal replacement therapy (HT) were included in the study. After one baseline night, three nights of sleep restricted to 4h were performed and were followed by one recovery night of 8h. Blood samplings were performed after the baseline night and after the third night of sleep restriction.
Results:
A significant increase in white blood cells (WBC), monocytes, neutrophils, total cholesterol, and low density lipoprotein cholesterol (LDL-c) was observed after the third night of sleep restriction.
Conclusion:
Sleep restriction to 4h of sleep for three consecutive nights affected two factors associated with cardiovascular risk in healthy postmenopausal women treated with HT.
Related Concept Videos
Cholesterol: Significance and Regulation
Considering cholesterol and...
Blood Studies for Cardiovascular System III: Serum Lipid Profile
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Lipids: Dietary Sources and Requirements
Atherosclerosis III: Management
Menopause
Insufficient Sleep and Sleep Deprivation
Sleep deprivation is a more severe form of sleep loss...