Related Experiment Video
Updated: Jul 20, 2026

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
Published on: September 22, 2020
Chronic snoring and sleep in children: a demonstration of sleep disruption
M Cecilia Lopes1, Christian Guilleminault
1Stanford University Sleep Medicine Program, Stanford, California, USA.
Insights
Children with chronic snoring, even without obstructive sleep apnea syndrome, show abnormal sleep patterns. These breathing issues can impact sleep quality and potentially affect learning and behavior.
Area of Science:
- Pediatric Sleep Medicine
- Respiratory Physiology
Background:
- Chronic snoring in children, not meeting obstructive sleep apnea syndrome criteria, is linked to potential learning and behavioral issues.
- Sleep-disordered breathing requires comprehensive evaluation beyond just the apnea-hypopnea index.
Purpose of the Study:
- To investigate the sleep structure and cyclic alternating pattern (CAP) in children with chronic snoring but a low apnea-hypopnea index (AHI).
- To analyze non-apneic-hypopneic breathing abnormalities and CAP characteristics in these children compared to controls.
Main Methods:
- Polysomnography was performed on 15 children with chronic snoring (AHI < 1) and 15 age-matched controls.
- Analysis included standard polysomnographic scoring and detailed examination of the cyclic alternating pattern (CAP).
Main Results:
- Chronic snorers exhibited flow limitations and tachypnea during sleep, despite normal oxygen saturation and absence of apneas/hypopneas.
- Abnormal CAP rates and alterations in CAP phase A were observed in snorers compared to controls.
Conclusions:
- The apnea-hypopnea index alone is insufficient for diagnosing sleep-disordered breathing in children.
- Children with chronic snoring and normal AHI can display abnormal sleep electroencephalograms, indicated by increased CAP rates, particularly during slow wave sleep.
Objective:
Chronic snoring that does not adhere to the criteria for a diagnosis of obstructive sleep apnea syndrome may be associated with learning and behavioral problems. We investigated the sleep structure of chronic snorers who had an apnea-hypopnea index of < 1 event per hour and analyzed the cyclic alternating pattern.
Methods:
Fifteen successively seen chronic snorers (9.8 +/- 4 years) with an apnea-hypopnea index of <1 and 15 aged-matched control subjects (10.3 +/- 5 years) underwent an investigation of their sleep with the determination of non-apneic-hypopneic breathing abnormalities polysomnographic scoring using current criteria and analysis of the cyclic alternating pattern.
Results:
Chronic snorers have evidence of flow limitations and tachypnea during sleep even if they do not present with apneas, hypopneas, and decrease in oxygen saturations. They also present with abnormal cyclic alternating pattern rates and changes in phase A of cyclic alternating pattern compared with control subjects.
Conclusions:
An apnea-hypopnea index value cannot be the sole determinant in evaluating sleep-disordered breathing in children. Children who have chronic snoring and do not respond to the criteria for obstructive sleep apnea syndrome can present with an abnormal sleep electroencephalogram as evidenced by a significant increase in cyclic alternating pattern rates, with a predominance of abnormalities in slow wave sleep.
Related Concept Videos
Sleep Apnea
The condition is more prevalent among...
Sleep-Wake Cycles
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
Nightmares and Night Terrors
Nightmares often...
REM Sleep Behavior Disorder
RBD is significantly associated with...
Narcolepsy
Insufficient Sleep and Sleep Deprivation
Sleep deprivation is a more severe form of sleep loss...

