Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diffusion-tensor magnetic resonance imaging in children with language impairment.

Jinna Kim1, Yong Wook Kim, Chang-Il Park

  • 1Department of Radiology and Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea.

Neuroreport
|September 5, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum to "A phase II clinical trial of paclitaxel-carboplatin as neoadjuvant therapy followed by surgery in patients with locally advanced head and neck squamous cell carcinoma" [Oral Oncol. 170 (2025) 107745].

Oral oncology·2026
Same author

[Preface to the Special Issue on 'Recent Updates in AJCC Staging of Head and Neck Cancer'].

Journal of the Korean Society of Radiology·2026
Same author

Human Papillomavirus-Positive Oropharyngeal Cancer: Clinical and Radiologic Characteristics.

Journal of the Korean Society of Radiology·2026
Same author

Risk of Parkinsonism After Exposure to Different Types of Gadolinium-Based Contrast Agents: A Nationwide Population-Based Cohort Study of 222,977 Individuals.

Korean journal of radiology·2026
Same author

Short-term outcomes and choroidal morphological changes following aflibercept therapy in pachychoroid neovasculopathy.

Scientific reports·2026
Same author

A phase II clinical trial of paclitaxel-carboplatin as neoadjuvant therapy followed by surgery in patients with locally advanced head and neck squamous cell carcinoma.

Oral oncology·2025
Same journal

Electroacupuncture alleviates neuroinflammation and promotes recovery of neurological functions after intracerebral hemorrhage by modulating α7nAChR/JAK2/STAT3 signaling pathway.

Neuroreport·2026
Same journal

Non-cell-autonomous regulation of Bhlhb5 expression in cortical projection neurons by GABAergic interneuron development and position.

Neuroreport·2026
Same journal

C-C motif chemokine ligand 3 mediates inflammatory response via NLRP3 inflammasome and neuron damage after traumatic brain injury.

Neuroreport·2026
Same journal

Methyltransferase-like 14 alleviates neuronal ferroptosis in Alzheimer's disease by regulating the peroxiredoxin 6/apoptosis signal-regulating kinase 1 signaling pathway.

Neuroreport·2026
Same journal

Hand mental rotation reaction time reflects motor imagery strategy and predicts changes in finger dexterity after motor imagery.

Neuroreport·2026
Same journal

Functional exploration of metabotropic glycine receptors in cultured rat hippocampal slices.

Neuroreport·2026
See all related articles

Diffusion tensor imaging revealed reduced white matter integrity in the genu of the corpus callosum in children with language impairments, suggesting delayed maturation contributes to their condition.

Area of Science:

  • Neuroimaging
  • Developmental Neuroscience
  • Speech and Language Pathology

Background:

  • Language impairments in children can have complex etiologies.
  • Conventional MRI may not detect subtle white matter abnormalities.
  • Diffusion tensor imaging (DTI) offers advanced insights into white matter microstructure.

Purpose of the Study:

  • To investigate white matter tract integrity in children with language impairments using DTI.
  • To compare DTI metrics between children with and without language impairments.
  • To identify specific white matter regions affected in pediatric language disorders.

Main Methods:

  • Diffusion tensor magnetic resonance imaging (DTI) was employed.
  • Fractional anisotropy (FA) values were measured in major white matter tracts.

Related Experiment Videos

  • Children with language impairments and age-matched controls were studied.
  • Analysis focused on six specific white matter tract locations.

    • Main Results:

    • Children with language impairments exhibited significantly reduced FA values.
    • The reduction in FA was specifically noted in the genu of the corpus callosum.
    • These subtle changes were not apparent on conventional MRI.
    • The genu of the corpus callosum is critical for interhemispheric communication.

    Conclusions:

    • Delayed white matter maturation may play a role in the pathophysiology of language impairments.
    • DTI is a valuable tool for detecting subtle white matter abnormalities in pediatric populations.
    • Targeted white matter development interventions could potentially benefit children with language disorders.