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Updated: Jul 20, 2026

Identifying Protein-protein Interaction Sites Using Peptide Arrays
Published on: November 18, 2014
Cluster properties of peptides on (100) semiconductor surfaces
Karsten Goede1, Marius Grundmann, Kai Holland-Nell
1Universität Leipzig, Institut für Experimentelle Physik II, Linnéstrasse 5, 04103 Leipzig, Germany. goede@physik.uni-leipzig.de
Abstract:
Peptide adhesion on semiconductor surfaces is quantitatively investigated by atomic force microscopy. The selected peptides are shown to cluster at the surface, with the larger, higher, and softer clusters appearing on the surfaces with lower peptide adhesion. Average cluster diameters vary from 40 nm on GaAs (100) to 300 nm on Si (100). Direct adhesion of the peptides to the surface competes with forming molecular aggregates that offer an overall reduced surface contact.
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