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Updated: Jul 20, 2026

Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol
Published on: February 21, 2016
Access to the kidney transplant wait list.
B Kiberd1, J Boudreault, V Bhan
1Department of Medicine, Dalhousie University, Halifax, Nova Scotia. bryce.kiberd@dal.ca
Older age, not comorbidity scores, significantly impacts kidney transplant referral and selection for end-stage renal disease (ESRD) patients. Many patients without contraindications are not referred, highlighting potential gaps in transplant access.
Area of Science:
- Nephrology
- Transplantation Medicine
- Healthcare Access
Background:
- Patient selection for kidney transplantation is complex.
- Understanding referral patterns and contraindications in end-stage renal disease (ESRD) is crucial for equitable access.
- The role of comorbidity indices in predicting transplant status requires further investigation.
Purpose of the Study:
- To examine kidney transplant selection processes.
- To identify factors influencing referral and contraindication status in ESRD patients.
- To determine if comorbidity indices predict transplant eligibility.
Main Methods:
- Retrospective analysis of 113 incident adult ESRD patients.
- Assessment of referral status based on published guidelines.
- Evaluation of contraindications and comorbidity indices (Charlson, ESRD).
- Comparison of 'Candidate' versus 'Neither' patient groups.
Main Results:
- 41.6% of ESRD patients were referred for kidney transplantation.
- 42.5% had a contraindication, while 23% were neither referred nor had contraindications.
- Age was the most significant discriminator between referred and non-referred patients without contraindications.
- ESRD mortality score predicted referral and contraindication status; comorbidity indices were less predictive.
Conclusions:
- Age is a key factor in kidney transplant selection, more so than comorbidity indices.
- A notable proportion of ESRD patients are not referred despite lacking contraindications.
- Further research is needed to assess the transplant benefit for 'Neither' patient group.
Related Concept Videos
Kidney Transplant I: Introduction
Kidney Transplant II: Surgical Procedure
Kidney Transplant III: Nursing Management
Tissue Transplantation
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
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Acute Kidney Injury IV: Diagnostic Studies and Prevention

