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A Murine Model of Irreversible and Reversible Unilateral Ureteric Obstruction
14:05

A Murine Model of Irreversible and Reversible Unilateral Ureteric Obstruction

Published on: December 20, 2014

Sclerosing mesenteritis progressing to ureteral obstruction

Scott Manatt1, Adam Metwalli, Daniel J Culkin

  • 1Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.

The Canadian Journal of Urology
|September 6, 2006
PubMed

Insights

Sclerosing mesenteritis, an inflammatory condition of the abdominal mesentery, can rarely involve the retroperitoneum. This case highlights its progression to ureteral involvement, a rare complication.

Area of Science:

  • Gastroenterology
  • Urology
  • Pathology

Background:

  • Sclerosing mesenteritis is a rare inflammatory condition affecting the abdominal mesentery.
  • It encompasses a spectrum of diseases including retractile mesenteritis, mesenteric panniculitis, and mesenteric lipodystrophy.
  • Retroperitoneal involvement is uncommon in sclerosing mesenteritis.

Observation:

  • A case of sclerosing mesenteritis is presented.
  • The disease exhibited progression.
  • Ureteral involvement was observed as a consequence of the disease progression.

Findings:

  • Sclerosing mesenteritis, a benign inflammatory disease, can manifest with unusual complications.
  • Retroperitoneal extension of sclerosing mesenteritis can lead to secondary ureteral compromise.
  • This case underscores the potential for sclerosing mesenteritis to impact adjacent retroperitoneal structures.

Implications:

  • Highlights the importance of considering sclerosing mesenteritis in the differential diagnosis of retroperitoneal and ureteral pathologies.
  • Suggests the need for vigilant monitoring for extra-abdominal complications in patients diagnosed with sclerosing mesenteritis.
  • Contributes to the understanding of the diverse clinical presentations and potential sequelae of sclerosing mesenteritis.

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