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[Lymphoma with initial renal involvement: four cases].

F-A Dauchy1, G Etienne, C Deminière

  • 1Médecine interne et maladies tropicales, hôpital Saint-André, CHU de Bordeaux, université Bordeaux-II, 1, rue Jean-Burguet, 33075 Bordeaux cedex, France. fadauchy@hotmail.com

La Revue De Medecine Interne
|September 6, 2006
PubMed
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Diagnosing lymphoma with kidney involvement is challenging, especially intravascular large B-cell lymphoma. Renal histology aided diagnosis in most cases, highlighting the need for awareness in renal manifestations of lymphoma.

Area of Science:

  • Nephrology
  • Oncology
  • Pathology

Background:

  • Lymphoma can present with diverse renal manifestations.
  • Early diagnosis of renal involvement in lymphoma is crucial for patient outcomes.

Observation:

  • A retrospective review identified four patients with lymphoma and kidney involvement.
  • Presentations included proteinuria, nephrotic syndrome, and renal masses.
  • Non-Hodgkin's lymphoma was diagnosed in all four patients.

Findings:

  • Intravascular large B-cell lymphoma was identified in one patient presenting with proteinuria.
  • Renal histology was diagnostic for lymphoma in three out of four cases.
  • Renal masses were observed in two patients.

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Implications:

  • The diagnosis of lymphoma with renal involvement is often difficult.
  • Increased clinical suspicion is warranted for primary renal lymphoma and intravascular large B-cell lymphoma.
  • Further research into the pathogenesis and diagnostic strategies for renal lymphoma is needed.