Related Experiment Video
Updated: Jul 20, 2026

Vessel-Sparing Microsurgical Longitudinal Intussusception Vasoepididymostomy to Treat Epididymal Obstructive Azoospermia
Published on: May 27, 2022
Embryos generated using testicular spermatozoa have higher developmental potential than those obtained using
Dmitri Dozortsev1, Rosa Neme, Michael P Diamond
1Clínica e Centro de Pesquisa em Reprodução Humana Roger Abdelmassih, São Paulo, Brazil. dmitri@dozortsev.net
Objective:
To determine whether the injection of testicular spermatozoa results in more viable embryos (higher implantation rate) than injection of epididymal spermatozoa in cases of obstructive azoospermia.
Design:
Retrospective analysis of 265 cases of testicular sperm aspiration (TESA) and percutaneous sperm aspiration (PESA), including 185 cases of obstructive azoospermia.
Setting:
Private Infertility clinic.
Patient(S):
None, charts review.
Intervention(S):
None, charts review.
Main Outcome Measure(S):
Clinical pregnancy rate (PR), implantation rate.
Result(S):
Although fertilization rates were higher in the PESA group, implantation rates were significantly better in the TESA group. There was also a trend to higher ongoing PR and lower miscarriage rates in TESA cases.
Conclusion(S):
In cases of obstructive azoospermia, embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa.
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