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Updated: Jul 20, 2026

Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
Published on: June 13, 2022
Progressive-convergent elucidation of stereochemistry in complex polyols. The absolute configuration of
Sarah C Lievens1, Tadeusz F Molinski
1Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, USA.
Abstract:
The absolute stereostructure of sagittamide A (1), a O-hexacetyl long-chain hexahydroxy-alpha,omega-dicarboxylic acid, was assigned using a progressive-convergent approach that integrates three powerful regimens for stereochemical analysis of acyclic natural products: J-based analysis, 13C NMR universal database comparisons, and exciton coupling circular dichroism.
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