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Updated: Jul 20, 2026
03:26
Detrusor Underactivity Model in Rats by Conus Medullaris Transection
Published on: August 28, 2020
Non-surgical treatment for detrusor overactivity
R Alexander Slack1, Simon Jackson
1Women's Centre, John Radcliffe Hospital, Oxford, UK. alexslack@ukonline.co.uk
The Journal of the British Menopause Society
|September 7, 2006
Summary
New treatments for urinary incontinence, including novel drugs and delivery methods, offer improved tolerability and effectiveness. This review examines these advancements, alongside anticholinergic agents, botulinum toxin, and neuromodulation for detrusor overactivity.
Area of Science:
- Urology
- Pharmacology
Background:
- Urinary incontinence affects approximately 17% of women due to detrusor overactivity.
- Traditional pharmacological treatments were limited by side effects and poor patient compliance.
Purpose of the Study:
- To review the effectiveness and tolerability of new pharmacotherapies for urinary incontinence.
- To discuss advancements in drug delivery and alternative treatments.
Main Methods:
- Literature review of recent pharmacological treatments for urinary incontinence.
- Assessment of new drugs, drug delivery systems, anticholinergic agents, botulinum toxin, and neuromodulation.
Main Results:
- Recent advancements have improved the tolerability and effectiveness of pharmacotherapy for urinary incontinence.
- New drugs and alternative delivery methods offer better patient compliance.
Conclusions:
- Novel treatments show promise in managing detrusor overactivity.
- Anticholinergic agents, botulinum toxin, and neuromodulation remain important therapeutic options.
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