Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Current developments in radiotherapy for paediatric brain tumours.

Roger E Taylor1

  • 1Clinical Oncology, South West Wales Cancer Institute, Singleton Hospital, Swansea, West Glamorgan, SA2 8QA, UK. R.E.Taylor@Swansea.ac.uk

European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society
|September 7, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction to: The effectiveness and safety of proton beam radiation therapy in children and young adults with Central Nervous System (CNS) tumours: a systematic review.

Journal of neuro-oncology·2024
Same author

The effectiveness and safety of proton beam radiation therapy in children and young adults with Central Nervous System (CNS) tumours: a systematic review.

Journal of neuro-oncology·2024
Same author

Assembling the brain trust: the multidisciplinary imperative in neuro-oncology.

Nature reviews. Clinical oncology·2019
Same author

Holistic approach is needed to evaluate potential benefits of proton beam therapy.

BMJ (Clinical research ed.)·2019
Same author

Outcomes of non-anaplastic stage III and 'inoperable' Wilms tumour treated in the UKW3 trial.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2019
Same author

The effectiveness and safety of proton beam radiation therapy in children with malignant central nervous system (CNS) tumours: protocol for a systematic review.

Systematic reviews·2016
Same journal

Not all acute peripheral facial palsy in children recovers completely: A telediagnostic follow-up study.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society·2026
Same journal

The prevalence of spinal muscular atrophy in Kazakhstan and the experience with the national nusinersen treatment program.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society·2026
Same journal

Motor-free visual perception and visuomotor integration in pediatric arterial ischemic stroke.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society·2026
Same journal

Familial, recurrent or genetic acute necrotizing encephalopathy of childhood: a systematic review and a case report. Focus on atypical events and on the role on immunizations.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society·2026
Same journal

Cenobamate in pediatric epilepsy: Moving beyond anecdotal experience.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society·2026
Same journal

Re: Diodato et al. "Distal arthrogryposis with impaired proprioception and touch: description of 9 additional cases harbouring novel PIEZO2 variants and literature review" (European Journal of Paediatric Neurology 61, 2026, 24-35).

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society·2026
See all related articles

Advances in radiation oncology, including hyperfractionated radiotherapy and precise delivery techniques, aim to improve pediatric brain tumor treatment by maximizing tumor dose while sparing healthy brain tissue.

Area of Science:

  • Pediatric Oncology
  • Radiation Oncology
  • Neuro-oncology

Background:

  • Childhood brain tumors are a significant challenge in pediatric oncology.
  • Traditional radiotherapy approaches have limitations in sparing normal brain tissue.
  • Understanding radiobiology is crucial for optimizing treatment outcomes.

Purpose of the Study:

  • To review recent advancements in radiation oncology for pediatric brain tumors.
  • To discuss the impact of these developments on treatment strategies.
  • To highlight the importance of minimizing long-term side effects.

Main Methods:

  • Review of current literature on radiation oncology techniques.
  • Analysis of improved understanding in radiobiology.
  • Evaluation of advanced radiotherapy planning and delivery systems.

Related Experiment Videos

  • Assessment of combined modality therapies (radiotherapy and drugs).

    • Main Results:

    • Hyperfractionated radiotherapy aims to enhance the therapeutic ratio.
    • Advanced techniques like 3D-CRT, IMRT, and proton therapy enable precise dose delivery and normal tissue sparing.
    • Combined modality treatments require careful toxicity evaluation.
    • Predictive models for radiotherapy dose-volume effects on neuropsychological function are emerging.

    Conclusions:

    • Precision radiotherapy techniques offer improved tumor targeting and reduced normal brain exposure.
    • Further research into combined therapies and predictive modeling is essential for optimizing pediatric brain tumor management.
    • Minimizing long-term neurocognitive morbidity is a key goal in pediatric radiation oncology.