Related Experiment Video
Updated: Jul 20, 2026

06:59
Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation
Published on: February 29, 2020
Retropharyngeal pseudomeningocele
S Achawal1, A Casey, G Etherington
1Department of Neurosurgery National Hospital for Neurology and Neurosurgery, Queen Square, UK. svachawal@hotmail.com
British Journal of Neurosurgery
|September 7, 2006
Summary
A rare retropharyngeal pseudomeningocele with C1-C2 dislocation was diagnosed post-mortem in a male patient. The condition
Area of Science:
- Neurosurgery
- Radiology
- Pathology
Background:
- Retropharyngeal pseudomeningoceles are rare collections of cerebrospinal fluid in the neck.
- Cervical spine dislocations, particularly at the C1-C2 level, can have severe neurological consequences.
Observation:
- A 38-year-old male presented with an undiagnosed retropharyngeal pseudomeningocele and C1-C2 dislocation.
- The patient's presentation was complicated by a lack of clear history and misleading circumstantial evidence.
- Concurrent medical issues overshadowed the spinal injury, leading to the patient's demise.
Findings:
- The retropharyngeal pseudomeningocele and C1-C2 dislocation were discovered incidentally after the patient's death.
- Preoperative diagnosis was impossible due to the rarity of the condition and atypical presentation.
- The patient's death prevented evaluation of the pseudomeningocele's clinical impact.
Implications:
- This case highlights the diagnostic challenges posed by rare cervical spine pathologies.
- It underscores the importance of considering unusual diagnoses even in the presence of common comorbidities.
- Further research into the etiology and management of retropharyngeal pseudomeningoceles is warranted.
Related Concept Videos
Hiatal Hernia
A hiatal hernia is the abnormal protrusion of the stomach or other abdominal organs through the esophageal hiatus of the diaphragm into the thoracic cavity.Normally, the gastroesophageal junction (GEJ) lies below the diaphragm and is supported by the phrenoesophageal membrane, the diaphragmatic crura, and connective tissues. Weakening of these structures—due to aging, congenital defects like a short esophagus, or increased intra-abdominal pressure from coughing, obesity, pregnancy, or heavy...
Esophageal Achalasia
Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide (VIP)...
Esophageal Perforation-II: Clinical Manifestations and Management
Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Clinical Manifestations:
Esophageal Perforation-I: Introduction
Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus.
The location of esophageal perforation can vary, occurring anywhere along the esophagus.
Pharynx
The pharynx, a tubular structure framed by skeletal muscle and lined with mucous membrane, extends continuously from the nasal cavities. It is segmented into three major areas: the nasopharynx, oropharynx, and laryngopharynx.
Nasopharynx
The nasopharynx, bordered by the conchae of the nasal cavity, serves exclusively as an air conduit. In its superior region, the pharyngeal tonsils or adenoids are located. These tonsils are clusters of lymphoid reticular tissue akin to a lymph node. The precise...
Nasopharynx
The nasopharynx, bordered by the conchae of the nasal cavity, serves exclusively as an air conduit. In its superior region, the pharyngeal tonsils or adenoids are located. These tonsils are clusters of lymphoid reticular tissue akin to a lymph node. The precise...
Bacterial Meningitis II: Pathophysiology
Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
