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Diagnosis of gastric syphilis by direct immunofluorescence staining and real-time PCR testing
Cheng-Yen Chen1, Kai-Hua Chi, Robert W George
1Division of STD Prevention, National Center for HIV, STD and TB Prevention, Centers for Disease Control and Prevention, Mail Stop G-39, 1600 Clifton Road, Atlanta, GA 30333, USA. cyc1@cdc.gov
Abstract:
We report on a case of gastric syphilis in a patient with chronic dyspepsia. The diagnosis was established by serology and the demonstration of spirochetes in diffusely inflammed gastric mucosa by staining with a fluorescent monoclonal antibody specific for pathogenic treponemes and by the detection of specific treponemal DNA sequences by a real-time PCR.

