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Related Concept Videos

Secondary Spinal Cord Injury llI: Pathophysiology01:25

Secondary Spinal Cord Injury llI: Pathophysiology

Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...
Spinal Cord Injury ll: Pathophysiology01:14

Spinal Cord Injury ll: Pathophysiology

Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...

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A Novel Vertebral Stabilization Method for Producing Contusive Spinal Cord Injury
09:24

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Published on: January 5, 2015

International Spinal Cord Injury Data Sets.

F Biering-Sørensen1, S Charlifue, M DeVivo

  • 1Clinic for Spinal Cord Injuries, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

Spinal Cord
|September 7, 2006
PubMed
Summary

This study outlines the development of International Spinal Cord Injury (SCI) Data Sets, establishing a standardized structure and terminology for consistent data collection and analysis in SCI research.

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Area of Science:

  • Rehabilitation Medicine
  • Clinical Data Standards

Background:

  • Standardized data collection is crucial for advancing spinal cord injury (SCI) research.
  • Previous efforts lacked a unified international approach to SCI data management.

Purpose of the Study:

  • To present the background, purpose, and process for developing International SCI Data Sets.
  • To establish a consensus-driven framework for SCI data collection.

Main Methods:

  • An international workshop was held in Vancouver, Canada, on May 2, 2002.
  • A process for selecting data elements for International SCI Data Sets was developed.
  • Consensus was reached on the structure and terminology for SCI data.

Main Results:

  • An overall structure and terminology aligned with the International Classification of Functioning, Disability and Health (ICF) was developed.
  • Definitions for a Core Data Set and additional Modules (Basic and Expanded) were established.
  • Guidelines for module development are being created, with working groups formed.

Conclusions:

  • The developed format provides a foundation for creating comprehensive SCI data sets and modules.
  • This standardization is expected to enhance the quality and comparability of SCI research globally.