Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Microbial interactions in Staphylococcus epidermidis biofilms.

Dietrich Mack1, Angharad P Davies, Llinos G Harris

  • 1Medical Microbiology and Infectious Diseases, The School of Medicine, Swansea University, Grove Building, Singleton Park, Swansea, SA2 8PP, UK. D.Mack@swansea.ac.uk

Analytical and Bioanalytical Chemistry
|September 7, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Head-to-head evaluation of a commercial real-time PCR assay targeting plasmodial species causing human malaria against a composite reference standard.

European journal of microbiology & immunology·2026
Same author

Comparative evaluation of EUCAST RAST and QuickMIC for rapid antimicrobial susceptibility testing of carbapenem-resistant organisms directly from positive blood cultures.

Microbiology spectrum·2026
Same author

Visible through touch: open-source 3D-printed tools for inclusive microbiology education.

Access microbiology·2026
Same author

Bacterial factors required for biofilm formation in <i>Staphylococcus epidermidis</i> are linked to contact activation.

Frontiers in cellular and infection microbiology·2026
Same author

Risk Factors for Discordance Between Synovial Fluid Culture and Intraoperative Cultures in Revision Arthroplasties: Results From a European Multicentre Observational Study.

JB & JS open access·2026
Same author

Activity of Cefepime/Enmetazobactam in Carbapenem-Resistant Gram-Negative Bacteria: Real-World Evidence from a German Tertiary Care Center.

Microbial drug resistance (Larchmont, N.Y.)·2026

Medical device infections caused by Staphylococcus epidermidis biofilms are a growing concern. Understanding biofilm formation and regulation, particularly quorum sensing, is key to developing new treatments.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Biomedical Engineering

Background:

  • Medical device-associated infections are a significant clinical challenge.
  • Coagulase-negative staphylococci, particularly Staphylococcus epidermidis, are primary causative agents.
  • Bacterial biofilm formation is central to the pathogenesis and recalcitrance of these infections to antibiotics.

Purpose of the Study:

  • To review the factors involved in Staphylococcus epidermidis biofilm elaboration.
  • To examine the regulatory mechanisms of biofilm expression, focusing on quorum sensing.
  • To highlight recent advancements that inform the development of novel medical strategies.

Main Methods:

  • Literature review of studies on Staphylococcus epidermidis biofilms.

Related Experiment Videos

  • Analysis of research on quorum sensing and gene regulation in biofilm formation.
  • Synthesis of findings to identify key pathogenic mechanisms.

    • Main Results:

    • Adherent, multilayered biofilms are critical for S. epidermidis pathogenesis.
    • Quorum sensing plays a crucial role in regulating biofilm development.
    • Understanding these mechanisms is advancing preventive and therapeutic approaches.

    Conclusions:

    • Significant progress has been made in understanding S. epidermidis biofilm formation.
    • Quorum sensing is a key target for intervention.
    • This knowledge underpins the development of improved diagnostic, therapeutic, and preventive measures for device-associated infections.