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T Cell Activation and Clonal Selection

T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...

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Related Experiment Video

Updated: Jul 5, 2026

Retroviral Transduction of T-cell Receptors in Mouse T-cells

Retroviral Transduction of T-cell Receptors in Mouse T-cells

Published on: October 22, 2010

The binary logic of antigen processing and presentation to T cells

J W Yewdell¹, J R Bennink

¹Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, Rockville, Maryland 20852.

|July 27, 1990

Summary

No abstract available in PubMed .

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