Changes of blood magnesium concentration in patients undergoing surgical myocardial revascularisation

Magnesium (Mg) is the second most relevant intracellular element, which plays an important role in many physiological processes. Magnesium disorders are particularly important in haemodynamically unstable patients, such as patients after extracorporeal circulation. The aim of this study was to analyze the changes in blood Mg levels in patients undergoing coronary artery bypass procedures with extracorporeal circulation.

Twenty male patients, aged 50-69, undergoing CABG with ECC under general anaesthesia, were included in the study. All of them were operated on due to Io and IIo degree coronary disease (according to CCS). The blood concentrations of Mg were examined in five stages: 1) before the induction of anaesthesia; 2) during extracorporeal circulation; 3) after surgery; 4) in the morning of the first postoperative day; 5) in the morning of the second postoperative day. The blood Mg concentrations were determined by spectrophotometric methods.

The blood concentration of Mg decreased during extracorporeal circulation and immediately after surgery and increased in the morning of the first and second postoperative days.

The CABG with extracorporeal circulation resulted in a significant decrease in blood Mg concentration.