Stereoselective functionalization of the 1'-position of 4'-thionucleosides
Prashantha Gunaga1, Hea Ok Kim, Hyuk Woo Lee
1Laboratory of Medicinal Chemistry, College of Pharmacy, Ewha Womans University, Seoul 120-750, Korea.
Organic Letters
|September 8, 2006
Abstract:
Stereoselective synthesis of novel 1'-alpha-substituted-4'-thionucleosides was achieved starting from D-gulonic acid gamma-lactone via stereoselective nucleophilic substitution.
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