Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Multiple post-chemotherapy plantar nevi].

Luis Hueso1, Celia Requena, Carlos Serra-Guillén

  • 1Servicio de Dermatología, Instituto Valenciano de Oncología, Valencia, España. luishueso@msn.com

Actas Dermo-Sifiliograficas
|September 8, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Superficial (Cutaneous) Tumors Exhibiting Morphological and Phenotypic Differentiation Toward Smooth Muscle and Pericytic Lineages.

International journal of surgical pathology·2026
Same author

Melanocortin-1 receptor variants and telomerase reverse transcriptase promoter mutations as prognostic biomarkers in stage IIB-IIC melanoma.

Melanoma research·2026
Same author

Lentigo Maligna Treated With Microscopically Controlled Surgery: A 194-Patient Retrospective Study.

International journal of dermatology·2026
Same author

DNA Repair Gene Polymorphisms as Genetic Factors Associated with Presence of Seborrheic Keratoses.

Dermatology (Basel, Switzerland)·2026
Same author

Diagnosis and treatment of cutaneous adverse effects of targeted therapy, antibody-drug conjugates, and immunotherapy in cancer patients: a national consensus statement by the Spanish Society of Medical Oncology and the Spanish Academy of Dermatology and Venereology.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2026
Same author

Sustainable Grape Antioxidant Dietary Fiber Preserves Proximal Colonic Homeostasis via Hsp27 and AMPK Signaling.

International journal of molecular sciences·2025
Same journal

Fingolimod-associated lymphomatoid papulosis.

Actas dermo-sifiliograficas·2026
Same journal

Demodicosis: update and treatment with laser and other light sources.

Actas dermo-sifiliograficas·2026
Same journal

New treatments for adult female acne.

Actas dermo-sifiliograficas·2026
Same journal

First regulations of the Spanish Society of Dermatology (1909).

Actas dermo-sifiliograficas·2026
Same journal

Long-hair FUE: advantages and disadvantages of the most recent technique in hair transplantation.

Actas dermo-sifiliograficas·2026
Same journal

Sunburns, Tanning, and Social Media: A Descriptive Study Among Spanish University Students.

Actas dermo-sifiliograficas·2026
See all related articles

Chemotherapy can cause new moles (melanocytic nevi) in children, likely due to immunosuppression. Close monitoring is recommended due to the increased melanoma risk associated with numerous moles.

Area of Science:

  • Dermatology
  • Pediatric Oncology
  • Immunology

Background:

  • Chemotherapy-induced immunosuppression is linked to various dermatological side effects in children.
  • Multiple melanocytic nevi have been observed following chemotherapy, suggesting an association with altered immune status rather than specific agents.

Observation:

  • A case report details a 12-year-old girl who developed numerous plantar melanocytic nevi after multidrug chemotherapy for acute lymphocytic leukemia.
  • The newly formed melanocytic nevi exhibited no concerning clinical features suggestive of malignancy.

Findings:

  • The development of multiple melanocytic nevi post-chemotherapy appears to be a consequence of the patient's immunosuppressed state.
  • While direct malignant transformation of these nevi to melanoma has not been reported, a high nevus count is a known melanoma risk factor.

Related Experiment Videos

Implications:

  • Close clinical surveillance of pediatric patients with multiple post-chemotherapy melanocytic nevi is warranted.
  • This highlights the importance of dermatological monitoring in pediatric cancer survivors.
  • Further research may elucidate the precise mechanisms linking immunosuppression and nevus development.