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Updated: Jul 20, 2026

The Antihypertensive Effects and Mechanisms of Huotan Jiedu Tongluo Decoction in Rats with H-Type Hypertension
Published on: May 17, 2024
Complicated hypertension related to the abuse of ephedrine and caffeine alkaloids
Jeffrey A Berman1, Arathi Setty, Matthew J Steiner
1Department of Psychiatry, UMDNJ-Robert Wood Johnson Medical School, 125 Patterson St, Suite 2200, New Brunswick, NJ 08901, USA. naadltc@aol.com
Abstract:
Ephedra containing products (ECPs), which most often contain additional sources of caffeine alkaloids, may be an under-recognized cause of hypertension. ECPs, especially when used in combination or at higher than recommended doses, can cause life-threatening cardiovascular and neurological complications. We present a case of hypertensive encephalopathy with new onset generalized tonic-clonic seizure secondary to concomitant use of two OTC supplements containing a mixture of ephedrine and caffeine alkaloids.
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