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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Related Experiment Video

Updated: Jul 20, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
09:37

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

A possible additional diagnostic tool for cutaneous melanoma.

Sarah Brenner1, Jacob Mashiah

  • 1Department of Dermatology, Tel Aviv-Sourasky Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. derma@tasmc.health.gov.il

Skinmed
|September 8, 2006
PubMed
Summary

Early detection of malignant melanoma is crucial. A reddish hue (erythema) near melanoma may indicate its presence and aid in treatment monitoring.

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Related Experiment Videos

Last Updated: Jul 20, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
09:37

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A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis
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Quantitative Visualization and Detection of Skin Cancer Using Dynamic Thermal Imaging
06:08

Quantitative Visualization and Detection of Skin Cancer Using Dynamic Thermal Imaging

Published on: May 5, 2011

Area of Science:

  • Dermatology
  • Oncology

Background:

  • Malignant melanoma incidence is rising, necessitating improved early detection methods.
  • The ABCD(E) rule aids in melanoma recognition, incorporating size, shape, color, and new features like erythema.

Purpose of the Study:

  • To investigate the significance of erythema as a potential indicator in malignant melanoma detection and prognosis.
  • To explore the relationship between erythema and growth factors in melanoma patients.

Main Methods:

  • Observational study analyzing skin changes in melanoma patients.
  • Biopsy analysis for vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) in relation to erythema.

Main Results:

  • 57% of melanoma patients exhibited adjacent erythema without distinct borders.
  • VEGF was positive in 50% of patients with erythema and 57% without.
  • PDGF was positive in 100% of patients with erythema versus 57% without.

Conclusions:

  • Adjacent erythema may serve as a clinical alert for malignant melanoma.
  • Erythema's association with growth factors suggests its role in melanoma progression or treatment response.