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Unusual macular lesions in a patient with neurofibromatosis type-1
Eibhlín M McLoone1, Trevor A S Buchanan
1Department of Ophthalmology, Royal Victoria Hospital, Grosvenor Road, Belfast, BT12 6BA, Northern Ireland. eibhlin_mcloone@hotmail.com
Background:
Retinal involvement in neurofibromatosis type-1 (NF-1) is rare.
Methods:
We present a case report of a 49-year-old man with neurofibromatosis who developed bilateral macular lesions associated with gradual reduction of visual acuity.
Results:
Electrophysiology revealed an absent pattern electroretinogram. Fluorescein angiography demonstrated mottled hyperfluorescence of the maculae in the early-phase fluorescein angiogram followed by late staining of the lesions.
Conclusions:
Our patient had unusual bilateral macular lesions which had some features suggestive of adult-onset foveomacular vitelliform dystrophy. To the best of our knowledge, there have been no previous reports of such macular lesions occurring in association with NF-1.
