From there to here: a personal viewpoint after three decades of neuropathy research

Currently there is unprecedented interest in research, writing, and clinical experience related to lower extremity peripheral nerve surgery. Its time is here, now. Application of the concepts for diagnosis and treatment of nerve compression, painful neuroma, and neuropathy has been a direct extension from the upper extremity to the lower extremity. By the end of 2005, there were more than a dozen studies demonstrating that the basic neuropathy causes metabolic changes that render the peripheral nerve susceptible to chronic nerve compressions. My hypothesis continues to assert that surgical decompression of known sites of compression can relieve symptoms of neuropathy that are caused by superimposed nerve compressions.