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Blood Transfusion and Agglutination

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...

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Related Experiment Video

Updated: Jul 20, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

Evidence-based decision making in transfusion medicine.

¹McMaster Transfusion Research Program, McMaster Uiversity, Canadian Blood Services, Hamilton, Ontario, Canada. heddlen@mcmaster.ca

|September 9, 2006

Summary

Evidence-based medicine (EBM) integration into daily clinical practice has evolved over 15 years. This paper outlines five key steps for effective evidence-based decision-making in healthcare.

Area of Science:

Medical Informatics
Clinical Decision Making
Health Services Research

Background:

Principles of evidence-based medicine (EBM) are long-standing.
The practical integration of EBM into daily clinical practice is a more recent development, evolving over the past 15 years.

Purpose of the Study:

To outline a structured approach for implementing evidence-based decision-making in clinical settings.
To detail the essential components of the EBM process for healthcare professionals.

Main Methods:

The paper focuses on five critical steps in evidence-based decision-making.
These steps include formulating well-defined questions, literature searching, critical appraisal of therapeutic articles, incorporating clinical expertise and patient values, and continuous quality improvement.

Related Experiment Videos

Last Updated: Jul 20, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

Main Results:

Effective EBM requires a systematic approach.
Key elements include question formulation, literature retrieval, critical appraisal, consideration of multifaceted factors, and ongoing process refinement.

Conclusions:

Implementing evidence-based decision-making is crucial for improving patient care.
A five-step framework facilitates the integration of EBM into routine clinical practice.