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Updated: Jul 20, 2026
14:59
Neuronavigation and Laparoscopy Guided Ventriculoperitoneal Shunt Insertion for the Treatment of Hydrocephalus
Published on: October 14, 2022
Hydrocephalus associated with Guillain-Barre syndrome
Chih-Yang Liu1, Chuen-Der Kao, Jen-Tse Chen
1Neurological Institute, Taipei Veterans General Hospital, Peitou District, Taipei, Taiwan.
Summary
Guillain-Barre syndrome (GBS) can rarely lead to normal pressure hydrocephalus, causing cognitive and motor deficits. Early brain imaging is crucial for GBS patients with neurological deterioration.
Area of Science:
- Neurology
- Immunology
Background:
- Guillain-Barre syndrome (GBS) is an autoimmune disorder affecting the peripheral nervous system.
- Influenza vaccination is a known, albeit rare, trigger for GBS.
Observation:
- A 68-year-old male presented with progressive weakness and areflexia post-influenza vaccination.
- Despite GBS treatment (plasmapheresis, immunoglobulin), the patient experienced persistent cognitive impairment, sleepiness, and motor disability.
- Brain imaging revealed normal pressure hydrocephalus.
Findings:
- Ventriculoperitoneal shunt insertion led to significant recovery of motor control and cognitive function.
- This case highlights a rare association between GBS and normal pressure hydrocephalus.
Implications:
- Routine brain imaging may be warranted in GBS patients exhibiting cognitive decline.
- Understanding this rare complication can improve diagnostic and therapeutic strategies for GBS.
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