Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Kidney Transplant I: Introduction

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...

Kidney Transplant II: Surgical Procedure

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...

Blood Transfusion

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...

Bone Marrow Sampling and Transplants

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...

Kidney Transplant III: Nursing Management

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...

The ABO Blood Group

The ABO Blood Group

The ABO blood group system is a critical element of transfusion medicine, essential for determining blood compatibility in transfusions and organ transplants. It is based on specific antigens, or agglutinogens, present on the surface of red blood cells (RBCs) and corresponding antibodies, or agglutinins, in the blood plasma.
Antigens in the ABO Blood Group System
Antigens are substances that can trigger an immune response, leading to the production of antibodies. In the ABO blood group system,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Ascitic Fluid Drainage Before Dialysis Catheter Removal for Peritoneal Dialysis-Related Peritonitis.

Kidney & blood pressure research·2026

Same author

Transcription Factor Ets-1 Is a Central Regulator of Redox Balance and Liver Regeneration Through epidermal growth factor (EGF) and transforming growth factor-β (TGF-β) 1 Signaling.

Laboratory investigation; a journal of technical methods and pathology·2026

Same author

Serum and tissue IGFBP2 as a prognostic biomarker in gastric adenocarcinoma: A multi-cohort clinical validation study.

Journal of the Formosan Medical Association = Taiwan yi zhi·2026

Same author

ZNRF1 deficiency disrupts Fas ligand trafficking and immune balance.

Cell death & disease·2026

Same author

Posttransplant screening and short-course treatment of latent tuberculosis infection in kidney transplant recipients: A prospective observational study in Taiwan.

Pulmonology·2026

Same author

Laparoscopic resection for high-risk gastric gastrointestinal stromal tumors: safety and oncological outcome.

Surgical endoscopy·2026

Search research articles

Related Experiment Video

Updated: Jul 20, 2026

Mouse Kidney Transplantation: Models of Allograft Rejection

Mouse Kidney Transplantation: Models of Allograft Rejection

Published on: October 11, 2014

Initial experience with ABO-incompatible live donor renal transplantation.

Meng-Kun Tsai¹, Ming-Hsiou Wu, Shyh-Chyl Lo

¹Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

Journal of the Formosan Medical Association = Taiwan Yi Zhi

|September 9, 2006

Summary

ABO-incompatible kidney transplants are now successful for patients needing organs. This involves new immunosuppressants, double filtration plasmapheresis (DFPP), and splenectomy to manage antibody levels and prevent rejection.

More Related Videos

Robot-Assisted Kidney Transplantation

Robot-Assisted Kidney Transplantation

Published on: July 19, 2021

Related Experiment Videos

Last Updated: Jul 20, 2026

Mouse Kidney Transplantation: Models of Allograft Rejection

Mouse Kidney Transplantation: Models of Allograft Rejection

Published on: October 11, 2014

Robot-Assisted Kidney Transplantation

Robot-Assisted Kidney Transplantation

Published on: July 19, 2021

Area of Science:

Nephrology
Transplantation Immunology

Background:

Severe shortage of cadaveric organs necessitates alternative kidney transplant strategies.
ABO-incompatible live donor renal transplantation offers a viable option for end-stage renal disease patients.

Observation:

Two cases of ABO-incompatible live donor renal transplantation are presented.
Patients received kidneys from blood group incompatible donors (A to AB, O to A).

Findings:

Preconditioning included tacrolimus, mycophenolate mofetil, and methylprednisolone.
Double filtration plasmapheresis (DFPP) effectively reduced anti-donor ABO antibodies.
Successful transplantation achieved with low serum creatinine levels post-procedure (1.0 and 1.4 mg/dL).

Implications:

ABO-incompatible renal transplantation is feasible with modern immunosuppression, DFPP, and splenectomy.
This approach expands options for patients with limited donor availability.
Successful outcomes demonstrate the potential to overcome blood group barriers in live donor kidney transplantation.