Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Considered judgement in evidence-based guideline development.

Karin Verkerk1, Haske Van Veenendaal, Johan L Severens

  • 1Dutch Institute for Healthcare Improvement (CBO), Utrecht, The Netherlands. k.verkerk@hro.nl

International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care
|September 9, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessing the association of physical distancing to avoid COVID-19 with health-related quality of life in immunocompromised adults: results from the cross-sectional observational EAGLE study.

BMJ public health·2026
Same author

Assessing the association of physical distancing to avoid COVID-19 with health-related quality of life in immunocompromised adolescents: results from the cross-sectional observational EAGLE study.

Frontiers in pediatrics·2026
Same author

Criteria to prioritize clinical practice guideline recommendations for patient decision aid development: results from a modified Delphi consensus study.

Journal of clinical epidemiology·2026
Same author

Preferences of healthcare providers regarding future follow-up care for breast, prostate, and colorectal cancer: A discrete choice experiment.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer·2026
Same author

Optimising personal continuity in general practice: process evaluation of a toolkit.

The British journal of general practice : the journal of the Royal College of General Practitioners·2026
Same author

The future is now: Towards intelligent use of Generative AI in general practice.

The European journal of general practice·2026

Experts reached consensus on 37 items to guide clinical guideline development when evidence is limited. This structured approach aids in formulating practical recommendations beyond scientific data.

Area of Science:

  • Health Policy and Research
  • Evidence-Based Medicine
  • Clinical Practice Guideline Development

Background:

  • Clinical practice guidelines (CPGs) rely on the best evidence, but this is often incomplete or controversial.
  • Formulating applicable recommendations requires considering factors beyond the available scientific evidence.

Purpose of the Study:

  • To achieve expert consensus on domains and items representing crucial 'other considerations' for CPG development.
  • To establish a framework for informed decision-making in evidence-based guideline formulation.

Main Methods:

  • Literature review to generate an initial list of 10 domains and 49 items.
  • Two-round Delphi consensus technique involving Dutch experts in guideline development.
  • Items reaching at least 60% consensus were included in the final list.

Related Experiment Videos

Main Results:

  • Twenty-eight experts participated in the first round, and 21 in the second.
  • Top-scoring domains included clinical relevance, safety, and resource availability.
  • Consensus was reached on 37 items; the 'conflicts of interest by industry' domain lacked consensus.

Conclusions:

  • This study presents the first formal consensus on structuring considered judgment in CPG recommendation development.
  • The finalized list of items can enhance the guideline development process.
  • Future research will focus on testing the practical utility and applicability of this list.