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Published on: November 9, 2018
Computed tomography findings in thiamine deficiency-induced coma
Andrea J Swenson1, Erik K St Louis
1Department of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA.
Neurocritical Care
|September 9, 2006
Summary
Noncontrast head computed tomography (CT) can reveal specific signs of coma. Acute fornices necrosis on CT is a new finding suggesting thiamine deficiency, a cause of Wernicke encephalopathy.
Area of Science:
- Neurology
- Radiology
- Nutritional Neuroscience
Background:
- Brain magnetic resonance imaging (MRI) is typically more sensitive for evaluating coma.
- Noncontrast head computed tomography (CT) can offer specific diagnostic clues in certain coma etiologies.
Observation:
- A case of coma induced by thiamine deficiency is presented.
- The patient exhibited acute necrosis of the fornices, visualized via CT scan.
Findings:
- Acute fornices necrosis represents a novel imaging finding on head CT.
- This finding is suggestive of thiamine deficiency, a key factor in Wernicke encephalopathy.
Implications:
- Head CT can be a valuable tool for diagnosing specific causes of coma, including Wernicke encephalopathy.
- Recognition of acute fornices necrosis on CT may expedite diagnosis and treatment of thiamine deficiency.
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