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Psoriasiform and palmoplanter pustular lesions induced after Kawasaki disease
Yuki Mizuno1, Yasushi Suga, Shigenori Muramatsu
1Department of Dermatology, Juntendo University School of Medicine, Tokyo, Japan.
International Journal of Dermatology
|September 12, 2006
Insights
Psoriatic lesions and pustules appeared in an infant after tuberculosis vaccination. This suggests a potential link between the Bacillus Calmette-Guérin vaccine and the development of these skin conditions.
Area of Science:
- Pediatric Dermatology
- Immunology
- Vaccinology
Background:
- Psoriasis is a chronic inflammatory skin condition.
- The Bacillus Calmette-Guérin (BCG) vaccine is widely used for tuberculosis prevention.
- Cutaneous adverse events following vaccination are rare but can occur.
Observation:
- A 7-month-old boy presented with psoriatic lesions on his face and arm.
- Lesions were noted at the site of BCG vaccination 4 months prior.
- Small pustules were observed on the palms and soles.
Findings:
- The clinical presentation suggests a potential association between BCG vaccination and the development of psoriatic lesions.
- The localized nature of the lesions at the vaccination site is a key observation.
- Disseminated pustules may indicate a systemic reaction.
Implications:
- This case highlights a possible, albeit rare, dermatological side effect of the BCG vaccine.
- Further investigation is warranted to understand the immunological mechanisms involved.
- Clinicians should be aware of potential vaccine-related skin manifestations in infants.
Abstract:
A 7-month-old boy was referred to us because of psoriatic lesions on the bilateral cheeks and on the extensor region of the left upper arm at the same site of his vaccination for tuberculosis 4 months previously (Fig. 1a,b). He also presented with small pustules scattered on the palms and soles (Fig. 1c).
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