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Updated: Jul 20, 2026

A Lip Fixation Device Facilitates Labial Salivary Gland Biopsy for Sjögren's Disease
Published on: March 6, 2026
Lingual traumatic ulceration (Riga-Fede disease)
Adone Baroni1, Carlo Capristo, Luigi Rossiello
1Department of Dermatology, 2nd University of Naples, Naples, Italy.
Abstract:
An 11-month-old male infant was referred to our clinic because of a painful ulcer of approximately 5 months' duration on the ventral surface of the tongue (Fig. 1). On physical examination, the lesion was circular (3 cm x 2 cm) with erythematous, raised, and indurated borders. No pathologic findings emerged from the laboratory data, neurologic examination, or clinical history. The family history was also negative for developmental disorders and congenital syndromes. No biopsy was performed in view of the age of the infant, the particular site of the lesion, and the clinical evidence of diagnosis. The treatment included odontologic cream (methylvinylether/maleic acid) as a protective shield, a collutorium (chlorhexidine 0.2%), and the use of a teething ring. Complete healing of the lesion (Fig. 2) occurred within 3 weeks.
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